Esterastin(CAS:67655-93-0)(分子式:C28H46N2O6)-生物分子-试剂-生物在线
上海甄准生物科技有限公司
Esterastin(CAS:67655-93-0)(分子式:C28H46N2O6)

Esterastin(CAS:67655-93-0)(分子式:C28H46N2O6)

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产品名称: Esterastin(CAS:67655-93-0)(分子式:C28H46N2O6)

英文名称: Esterastin

产品编号: TRC-E668400

产品价格: 0

产品产地: CANADA

品牌商标: TRC

更新时间: null

使用范围: null

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1) Cat. No.: TRC-E668400; 2) Chemical Name: Esterastin; 3) CAS No.: 67655-93-0; 4) Mol. Formula: C28H46N2O6; 5) Mol. Weight: 506.67; 6) Packing Size: 5mg / 50mg; 7) Appearence: ; 8) Application Notes: Esterastin is a potent inhibitor of lysosomal acid lipase. Esterastin inhibited the enzyme activity very strongly (IC50, about 80 nM). The inhibition of acid lipase by Esterastin was competitive with respect to the substrate and the inhibition constant for Esterastin was 90 nM. Esterastin was less inhibitory to other lipolytic enzymes, such as pancreatic lipase and carboxylesterase. Thus, Esterastin is a potent new inhibitor of lysosomal acid lipase. ; 9) Synonym: N2-Acetyl-L-asparagine (1S,3Z,6Z)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]
methyl]-3,6-dodecadien-1-yl Ester; 
[2S-[2α(1R*,3Z,6Z),3β]]-N2-Acetyl-L-asparagine 1-[(3-Hexyl-4-oxo-2-oxetanyl)
methyl]-3,6-dodecadienyl Ester;  ; 10) Solubility: ; 11) Storage condition: ; 12) References: Ecsedi, G.G., et al.: Biochem. Internat.,10,337 (1985); Imanaka, T., et al.: J. Biochem.,94, 1017 (1983);