Recombinant Rat Interleukin-17A (Rat IL-17A)
产品名称: Recombinant Rat Interleukin-17A (Rat IL-17A)
英文名称: Recombinant Rat Interleukin-17A (Rat IL-17A)
产品编号: 90177ES08
产品价格: 0
产品产地: Yeasen
品牌商标: Yeasen
更新时间: 2025-02-05T17:21:42
使用范围: null
规格 | 价格 |
5 μg | 415.0 |
25μg | 1285.0 |
100 μg | 3215.0 |
1mg | 16915.0 |
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Product Information
Product Name
Cat#
Size
Recombinant Rat Interleukin-17A (Rat IL-17A)
90177ES08
5 μg
90177ES25
25 μg
90177ES60
100 μg
90177ES80
1 mg
Product Description
Interleukin-17A (IL-17A), also known as CTLA-8, is a glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold. Mature rat IL-17A shares 60% and 89% amino acid sequence identity with human and mouse IL-17A, respectively. IL-17A is secreted by Th17 cells, gamma /δ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells.
Product Properties
Synonyms
CTLA8; CTLA-8
Accession
Q61453
Unigene
Rn.218513.
Source
E.coli-derived Rat IL-17A,Ala18-Ser150.
Molecular Weight
Approximately 30.0 kDa.
AA Sequence
AVLIPQSSVC PNAEANNFLQ NVKVNLKVIN SLSSKASSRR PSDYLNRSTS PWTLSRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPEKCPFT FRVEKMLVGV GCTCVSSIVR HAS
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Biological Activity
The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 1.0 ng/mL, corresponding to a specific activity of > 1.0 × 106 IU/mg. Fully biologically active when compared to standard.
Endotoxin
< 0.1 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 µm filtered concentrated solution in 2 × PBS, pH 6.5.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
- Avoid repeated freeze-thaw cycles.
- For your safety and health, please wear lab coats and disposable gloves for operation.
- 3. For research use only!
HB240523